Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04AGG
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| Drug Name |
Favipiravir
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| Synonyms |
AIDS121660; Favipiravir (JAN/INN); 3-bromo-5-hydroxy-4-methyl-2,6-dinitro-benzoic Acid; T705
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| Drug Type |
Small molecular drug
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| Indication | Influenza virus infection [ICD-11: 1E30-1E32] | Approved | [1] | |
| Coronavirus Disease 2019 (COVID-19) [ICD-11: 1D6Y] | Phase 3 | [2], [3] | ||
| Therapeutic Class |
Antiviral Agents
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| Company |
Toyama Chemical
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| Structure |
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Download2D MOL |
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| Formula |
C5H4FN3O2
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| Canonical SMILES |
C1=C(N=C(C(=O)N1)C(=O)N)F
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| InChI |
1S/C5H4FN3O2/c6-2-1-8-5(11)3(9-2)4(7)10/h1H,(H2,7,10)(H,8,11)
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| InChIKey |
ZCGNOVWYSGBHAU-UHFFFAOYSA-N
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| CAS Number |
CAS 259793-96-9
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:134722
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | COVID-19 RNA-directed RNA polymerase (RdRp) | Target Info | Inhibitor | [4], [5] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | ClinicalTrials.gov (NCT04336904) Clinical Study To Evaluate The Performance And Safety Of Favipiravir in COVID-19 | |||
| REF 3 | ChiCTR.org.cn (ChiCTR2000030254) the Efficacy and Safety of Favipiravir for novel coronavirusinfected pneumonia: A multicenter, randomized, open, positive, parallel-controlled clinical study | |||
| REF 4 | Favipiravir versus Arbidol for COVID-19: A Randomized Clinical Trial. medRxiv. Posted April 15, 2020. | |||
| REF 5 | Therapeutic options for the 2019 novel coronavirus (2019-nCoV). Nat Rev Drug Discov. 2020 Mar;19(3):149-150. | |||
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