Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03TPR
|
|||
| Drug Name |
Dextrothyroxine Sodium
|
|||
| Synonyms |
Choloxin
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | High blood cholesterol level [ICD-11: 5C80.00; ICD-10: E78.0] | Approved | [1] | |
| Company |
Abbvie Inc
|
|||
| Structure |
 |
Download2D MOL
|
||
| Formula |
C15H10I4NNaO4
|
|||
| Canonical SMILES |
C1=C(C=C(C(=C1I)OC2=CC(=C(C(=C2)I)O)I)I)CC(C(=O)[O-])N.[Na+]
|
|||
| InChI |
1S/C15H11I4NO4.Na/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;/h1-2,4-5,12,21H,3,20H2,(H,22,23);/q;+1/p-1/t12-;/m1./s1
|
|||
| InChIKey |
YDTFRJLNMPSCFM-UTONKHPSSA-M
|
|||
| CAS Number |
CAS 137-53-1
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Thyroid hormone receptor alpha (THRA) | Target Info | Modulator | [2] |
| Thyroid hormone receptor beta (THRB) | Target Info | Modulator | [2] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Thyroid hormone signaling pathway | ||||
| Pathway Interaction Database | RXR and RAR heterodimerization with other nuclear receptor | |||
| Reactome | Nuclear Receptor transcription pathway | |||
| WikiPathways | Endochondral Ossification | |||
| Nuclear Receptors | ||||
| SIDS Susceptibility Pathways | ||||
| Hematopoietic Stem Cell Differentiation | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.