Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03QKF
|
|||
| Former ID |
DNC010575
|
|||
| Drug Name |
2-(3-(3,5-dichlorophenyl)ureido)benzoic acid
|
|||
| Synonyms |
CHEMBL1088742; 2-{[(3,5-dichlorophenyl)carbamoyl]amino}benzoic acid; 2-(3-(3,5-dichlorophenyl)ureido)benzoic acid; SCHEMBL11983339; MolPort-011-309-281; BDBM50313600; AKOS012857299
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C14H10Cl2N2O3
|
|||
| Canonical SMILES |
C1=CC=C(C(=C1)C(=O)O)NC(=O)NC2=CC(=CC(=C2)Cl)Cl
|
|||
| InChI |
1S/C14H10Cl2N2O3/c15-8-5-9(16)7-10(6-8)17-14(21)18-12-4-2-1-3-11(12)13(19)20/h1-7H,(H,19,20)(H2,17,18,21)
|
|||
| InChIKey |
PIWYMPXOKMFVER-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Plasmodium Dihydroorotate dehydrogenase (Malaria DHOdehase) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Pyrimidine metabolism | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Pyrimidine Metabolism | |||
| Reactome | Pyrimidine biosynthesis | |||
| WikiPathways | Metabolism of nucleotides | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Discovery of novel inhibitors for DHODH via virtual screening and X-ray crystallographic structures. Bioorg Med Chem Lett. 2010 Mar 15;20(6):1981-4. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.