Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03PLQ
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| Drug Name |
Benzothiazole analog 3
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| Synonyms |
PMID26815044-Compound-38
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| Drug Type |
Small molecular drug
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| Indication | Albinism [ICD-11: EC23.2; ICD-10: E70.3, H90.3] | Patented | [1] | |
| Ephelides [ICD-11: ED61.0] | Patented | [1] | ||
| Melasma [ICD-11: ED60.1] | Patented | [1] | ||
| Menkes disease [ICD-11: 5C64.0; ICD-10: E83.0] | Patented | [1] | ||
| Senile lentigines [ICD-11: ED61.0] | Patented | [1] | ||
| Structure |
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Download2D MOL |
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| Formula |
C24H23N3O3S3
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| Canonical SMILES |
CC1=CC2=C(C=C1)N=C(S2)C3=CC=C(C=C3)NC(=O)C4CCN(CC4)S(=O)(=O)C5=CC=CS5
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| InChI |
1S/C24H23N3O3S3/c1-16-4-9-20-21(15-16)32-24(26-20)18-5-7-19(8-6-18)25-23(28)17-10-12-27(13-11-17)33(29,30)22-3-2-14-31-22/h2-9,14-15,17H,10-13H2,1H3,(H,25,28)
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| InChIKey |
IVGKSFUEBSXSAE-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tyrosinase (TYR) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Tyrosinase (TYR) | Target's Patent Info | [1] | |
| BioCyc | (S)-reticuline biosynthesis | |||
| Eumelanin biosynthesis | ||||
| L-dopachrome biosynthesis | ||||
| KEGG Pathway | Tyrosine metabolism | |||
| Riboflavin metabolism | ||||
| Metabolic pathways | ||||
| Melanogenesis | ||||
| Pathwhiz Pathway | Riboflavin Metabolism | |||
| Tyrosine Metabolism | ||||
| WikiPathways | Dopamine metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Tyrosinase inhibitors: a patent review (2011-2015).Expert Opin Ther Pat. 2016;26(3):347-62. | |||
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