Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03MWZ
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| Former ID |
DIB009995
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| Drug Name |
Syntropin
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| Synonyms |
Human growth hormone (subcutaneous, dwarfism), Phage Biotechnology
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| Indication | Dwarfism [ICD-11: 5B11; ICD-10: E34.3] | Phase 1 | [1] | |
| Company |
Phage Biotechnology Corp
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Growth hormone receptor (GHR) | Target Info | Modulator | [2] |
| KEGG Pathway | Cytokine-cytokine receptor interaction | |||
| Neuroactive ligand-receptor interaction | ||||
| PI3K-Akt signaling pathway | ||||
| Jak-STAT signaling pathway | ||||
| Pathway Interaction Database | Notch-mediated HES/HEY network | |||
| Reactome | Prolactin receptor signaling | |||
| Growth hormone receptor signaling | ||||
| WikiPathways | Endochondral Ossification | |||
| Prolactin receptor signaling | ||||
| Growth hormone receptor signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT00489294) Safety Study of Syntropin (Human Growth Hormone) for the Treatment of Growth Hormone Deficiency. U.S. National Institutes of Health. | |||
| REF 2 | Late feedback effects of hypothalamic-pituitary-adrenal axis hormones in healthy subjects. Psychoneuroendocrinology. 1998 May;23(4):371-83. | |||
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