Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03JZQ
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| Former ID |
DNC010786
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| Drug Name |
3-(4-phenyl-6-(thiophen-3-yl)pyridin-2-yl)-phenol
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| Synonyms |
CHEMBL1095140
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C21H15NOS
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| Canonical SMILES |
C1=CC=C(C=C1)C2=CC(=NC(=C2)C3=CSC=C3)C4=CC(=CC=C4)O
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| InChI |
1S/C21H15NOS/c23-19-8-4-7-16(11-19)20-12-18(15-5-2-1-3-6-15)13-21(22-20)17-9-10-24-14-17/h1-14,23H
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| InChIKey |
GZCPVCLLSOKGCF-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | DNA topoisomerase I (TOP1) | Target Info | Inhibitor | [1] |
| DNA topoisomerase II (TOP2) | Target Info | Inhibitor | [1] | |
| NetPath Pathway | IL2 Signaling Pathway | |||
| Panther Pathway | DNA replication | |||
| Pathway Interaction Database | Caspase Cascade in Apoptosis | |||
| WikiPathways | Integrated Pancreatic Cancer Pathway | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of hydroxylated 2,4-diphenyl-6-aryl ... Bioorg Med Chem. 2010 May 1;18(9):3066-77. | |||
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