Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D02WUU
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| Former ID |
DNC007980
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| Drug Name |
2-(phenylsulfonyl)-1-p-tolylethanone
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| Synonyms |
38488-14-1; CHEMBL392808; Ethanone, 1-(4-methylphenyl)-2-(phenylsulfonyl)-; 2-(phenylsulfonyl)-1-p-tolylethanone; 4-Methylphenacylphenyl sulfone; SCHEMBL6202982; CTK1A8876; DTXSID20575987; BDBM50212530; ZINC28874639; AKOS008967833; 1-p-Tolyl-2-(phenylsulphonyl)ethanone; 1-(4-methylphenyl)-2-(phenylsulfonyl)ethanone; 2-(Benzenesulfonyl)-1-(4-methylphenyl)ethan-1-one
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H14O3S
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| Canonical SMILES |
CC1=CC=C(C=C1)C(=O)CS(=O)(=O)C2=CC=CC=C2
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| InChI |
1S/C15H14O3S/c1-12-7-9-13(10-8-12)15(16)11-19(17,18)14-5-3-2-4-6-14/h2-10H,11H2,1H3
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| InChIKey |
DITVWQPTRBYVRP-UHFFFAOYSA-N
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| CAS Number |
CAS 38488-14-1
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Corticosteroid 11-beta-dehydrogenase 1 (HSD11B1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolism of xenobiotics by cytochrome P450 | ||||
| Metabolic pathways | ||||
| Chemical carcinogenesis | ||||
| NetPath Pathway | IL1 Signaling Pathway | |||
| FSH Signaling Pathway | ||||
| Pathwhiz Pathway | Steroidogenesis | |||
| Reactome | Glucocorticoid biosynthesis | |||
| WikiPathways | Prostaglandin Synthesis and Regulation | |||
| Metabolism of steroid hormones and vitamin D | ||||
| Glucocorticoid & Mineralcorticoid Metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | beta-Keto sulfones as inhibitors of 11beta-hydroxysteroid dehydrogenase type I and the mechanism of action. Bioorg Med Chem. 2007 Jul 1;15(13):4396-405. | |||
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