Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D02COM
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| Former ID |
DNC000104
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| Drug Name |
7-tert-butyl-2, 3-dihydro-3, 3-dimethyl substituted dihydrofuran 30 (DHDMBF30)
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| Synonyms |
Hemicholinium; 16478-59-4; 2,2'-(Biphenyl)-4,4'-diylbis(2-hydroxy-4,4-dimethylmorpholinium); 2,2'-(4,4'-Biphenylene)bis(2-hydroxy-4,4-dimethylmorpholinium); 2-[4-[4-(2-hydroxy-4,4-dimethylmorpholin-4-ium-2-yl)phenyl]phenyl]-4,4-dimethylmorpholin-4-ium-2-ol; Morpholinium, 2,2'-(4,4'-biphenylene)bis(2-hydroxy-4,4-dimethyl-; Prestwick3_000393; Prestwick0_000393; Prestwick1_000393; Prestwick2_000393; AC1L1G9B; Lopac0_000578; BSPBio_000605; SPBio_002526; CHEMBL268697; BPBio1_000667; GTPL4494; SCHEMBL12638596; 8-amino-5'-deoxy-5'-chloroguanosine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1], [2], [3] | |
| Structure |
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Download2D MOL |
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| Formula |
C24H34N2O4+2
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| Canonical SMILES |
C[N+]1(CCOC(C1)(C2=CC=C(C=C2)C3=CC=C(C=C3)C4(C[N+](CCO4)(C)C)O)O)C
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| InChI |
1S/C24H34N2O4/c1-25(2)13-15-29-23(27,17-25)21-9-5-19(6-10-21)20-7-11-22(12-8-20)24(28)18-26(3,4)14-16-30-24/h5-12,27-28H,13-18H2,1-4H3/q+2
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| InChIKey |
JIWUESGGKYLPPG-UHFFFAOYSA-N
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| CAS Number |
CAS 16478-59-4
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| PubChem Compound ID | ||||
| PubChem Substance ID |
7440465, 8152261, 11466421, 11467541, 11486262, 26756595, 29222711, 47365421, 47365422, 47885612, 48185192, 48259465, 49698469, 49994532, 50070722, 50111083, 50381698, 57321877, 85209525, 90341031, 103107979, 103170774, 104303932, 114916412, 117613891, 124749826, 124880252, 128281574, 129212665, 134339628, 134339629, 134340080, 135073722, 136351306, 137008799, 141867156, 142312972, 160849790, 162800225, 178101222, 179236191, 237684190
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| ChEBI ID |
CHEBI:94343
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | Novel molecular targets for antimalarial drug development. Chem Biol Drug Des. 2008 Apr;71(4):287-97. | |||
| REF 2 | Effect of 5-LOX/COX-2 common inhibitor DHDMBF30 on pancreatic cancer cell Capan2. World J Gastroenterol. 2008 Apr 28;14(16):2494-500. | |||
| REF 3 | Expression of human malaria parasite purine nucleoside phosphorylase in host enzyme-deficient erythrocyte culture. Enzyme characterization and identification of novel inhibitors. J Biol Chem. 1986 Sep 5;261(25):11667-73. | |||
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