Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01NTI
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| Former ID |
DNC005311
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| Drug Name |
N*2*-Benzyl-N*6*-cyclohexyl-9H-purine-2,6-diamine
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| Synonyms |
CHEMBL190147; N*2*-Benzyl-N*6*-cyclohexyl-9H-purine-2,6-diamine; BDBM50170836
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C18H22N6
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| Canonical SMILES |
C1CCC(CC1)NC2=NC(=NC3=C2NC=N3)NCC4=CC=CC=C4
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| InChI |
1S/C18H22N6/c1-3-7-13(8-4-1)11-19-18-23-16-15(20-12-21-16)17(24-18)22-14-9-5-2-6-10-14/h1,3-4,7-8,12,14H,2,5-6,9-11H2,(H3,19,20,21,22,23,24)
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| InChIKey |
NPPHTZNKBUCRPG-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adenosine A3 receptor (ADORA3) | Target Info | Inhibitor | [1] |
| Reactome | Adenosine P1 receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Nucleotide GPCRs | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Reversine and its 2-substituted adenine derivatives as potent and selective A3 adenosine receptor antagonists. J Med Chem. 2005 Jul 28;48(15):4910-8. | |||
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