Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01ISX
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| Former ID |
DNC009938
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| Drug Name |
4-[2-(2-Thienyl)acetamidoethyl]benzenesulfonamide
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| Synonyms |
ST044176; N-[2-(4-sulfamoylphenyl)ethyl]-2-(2-thienyl)acetamide; N-[2-(4-sulfamoylphenyl)ethyl]-2-(thiophen-2-yl)acetamide; N-[2-(4-Sulfamoyl-phenyl)-ethyl]-2-thiophen-2-yl-acetamide; 6613-83-8; NAPETA; sulfonamide deriv., 5f; AC1LDO3N; Oprea1_814072; Oprea1_120836; MLS001207920; CHEMBL583171; ZINC31727; BDBM35731; DTXSID20350014; MolPort-001-528-371; HMS2823O10; STK091085; AKOS000648562; MCULE-3510388823; BAS 03034092; 349537-90-2; SMR000518099; MLS-0291936.0001; SR-01000476637; SR-01000476637-1; Z30857856
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C14H16N2O3S2
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| Canonical SMILES |
C1=CSC(=C1)CC(=O)NCCC2=CC=C(C=C2)S(=O)(=O)N
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| InChI |
1S/C14H16N2O3S2/c15-21(18,19)13-5-3-11(4-6-13)7-8-16-14(17)10-12-2-1-9-20-12/h1-6,9H,7-8,10H2,(H,16,17)(H2,15,18,19)
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| InChIKey |
DWGJCBRJYFGGNR-UHFFFAOYSA-N
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| CAS Number |
CAS 6613-83-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Carbonic anhydrase (CA) | Target Info | Inhibitor | [1] |
| Carbonic anhydrase I (CA-I) | Target Info | Inhibitor | [1] | |
| Carbonic anhydrase II (CA-II) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Nitrogen metabolism | |||
| Proximal tubule bicarbonate reclamation | ||||
| Collecting duct acid secretion | ||||
| Gastric acid secretion | ||||
| Pancreatic secretion | ||||
| Bile secretion | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| EGFR1 Signaling Pathway | ||||
| Pathwhiz Pathway | Gastric Acid Production | |||
| Pathway Interaction Database | C-MYB transcription factor network | |||
| Reactome | Erythrocytes take up carbon dioxide and release oxygen | |||
| Erythrocytes take up oxygen and release carbon dioxide | ||||
| Reversible hydration of carbon dioxide | ||||
| WikiPathways | Reversible Hydration of Carbon Dioxide | |||
| Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes | ||||
| Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Carbonic anhydrase inhibitors. Aromatic/heterocyclic sulfonamides incorporating phenacetyl, pyridylacetyl and thienylacetyl tails act as potent inh... Bioorg Med Chem. 2009 Jul 15;17(14):4894-9. | |||
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