Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D01ICI
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| Drug Name |
Remdesivir
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| Synonyms |
L-Alanine, N-((S)-hydroxyphenoxyp; RWWYLEGWBNMMLJ-YSOARWBDSA-N; Remdesivir [USAN]; 1809249-37-3; 3QKI37EEHE; AKOS032946252; SB19838; SCHEMBL17712225; UNII-3QKI37EEHE
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| Drug Type |
Small molecular drug
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| Indication | Coronavirus Disease 2019 (COVID-19) [ICD-11: 1D6Y] | Approved | [1] | |
| Ebola virus infection [ICD-11: 1D60.0] | Phase 1 | [2] | ||
| Company |
Gilead Sciences, Foster City, CA
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| Structure |
 |
Download2D MOL |
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| Formula |
C27H35N6O8P
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| Canonical SMILES |
CCC(CC)COC(=O)C(C)NP(=O)(OCC1C(C(C(O1)(C#N)C2=CC=C3N2N=CN=C3N)O)O)OC4=CC=CC=C4
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| InChI |
1S/C27H35N6O8P/c1-4-18(5-2)13-38-26(36)17(3)32-42(37,41-19-9-7-6-8-10-19)39-14-21-23(34)24(35)27(15-28,40-21)22-12-11-20-25(29)30-16-31-33(20)22/h6-12,16-18,21,23-24,34-35H,4-5,13-14H2,1-3H3,(H,32,37)(H2,29,30,31)/t17-,21+,23+,24+,27-,42-/m0/s1
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| InChIKey |
RWWYLEGWBNMMLJ-YSOARWBDSA-N
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| CAS Number |
CAS 1809249-37-3
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:145994
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | COVID-19 RNA-directed RNA polymerase (RdRp) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2020 | |||
| REF 2 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
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