Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D01HAZ
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| Former ID |
DNC007836
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| Drug Name |
3-(dibutylamino)-1-(4-hexylphenyl)propan-1-one
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| Synonyms |
beta-Aminophenylketone, 3g; 3-(dibutylamino)-1-(4-hexylphenyl)propan-1-one; CHEMBL396086; SCHEMBL15862326; BDBM18820
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C23H39NO
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| Canonical SMILES |
CCCCCCC1=CC=C(C=C1)C(=O)CCN(CCCC)CCCC
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| InChI |
1S/C23H39NO/c1-4-7-10-11-12-21-13-15-22(16-14-21)23(25)17-20-24(18-8-5-2)19-9-6-3/h13-16H,4-12,17-20H2,1-3H3
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| InChIKey |
UMFRWWULZNWTFF-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Thyroid hormone receptor alpha (THRA) | Target Info | Inhibitor | [1] |
| Thyroid hormone receptor beta (THRB) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Thyroid hormone signaling pathway | ||||
| Pathway Interaction Database | RXR and RAR heterodimerization with other nuclear receptor | |||
| Reactome | Nuclear Receptor transcription pathway | |||
| WikiPathways | Endochondral Ossification | |||
| Nuclear Receptors | ||||
| SIDS Susceptibility Pathways | ||||
| Hematopoietic Stem Cell Differentiation | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Inhibitors of the interaction of a thyroid hormone receptor and coactivators: preliminary structure-activity relationships. J Med Chem. 2007 Nov 1;50(22):5269-80. | |||
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