Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01FTB
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| Former ID |
DNC014057
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| Drug Name |
2-(4-chlorophenyl)-4,5-dihydro-1H-imidazole
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| Synonyms |
2-(4-chlorophenyl)-4,5-dihydro-1H-imidazole; 13623-52-4; CHEMBL448710; 1H-Imidazole,2-(4-chlorophenyl)-4,5-dihydro-; NSC129258; AC1L5PGD; AC1Q3R0Q; AC1Q3IU9; 1h-imidazole, 2-(4-chlorophenyl)-4,5-dihydro-; SCHEMBL523059; CTK4C0220; DTXSID90299300; XUMWMBLBTZAVLW-UHFFFAOYSA-N; MolPort-005-311-522; ZINC608390; 2-(4-chlorophenyl)-2-imidazoline; 2-(4-Chlorophenyl)-1-imidazoline; BDBM50266028; STK367850; AKOS005444786; NE32890; NSC-129258; MCULE-4125153952; 2-Imidazoline, 2-(p-chloro-phenyl)-; DB-063124; FT-0766187; EN300-29599
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C9H9ClN2
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| Canonical SMILES |
C1CN=C(N1)C2=CC=C(C=C2)Cl
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| InChI |
1S/C9H9ClN2/c10-8-3-1-7(2-4-8)9-11-5-6-12-9/h1-4H,5-6H2,(H,11,12)
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| InChIKey |
XUMWMBLBTZAVLW-UHFFFAOYSA-N
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| CAS Number |
CAS 13623-52-4
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Monoamine oxidase type B (MAO-B) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of tryptophan utilization | |||
| Tryptophan degradation via tryptamine | ||||
| Dopamine degradation | ||||
| Putrescine degradation III | ||||
| Noradrenaline and adrenaline degradation | ||||
| KEGG Pathway | Glycine, serine and threonine metabolism | |||
| Arginine and proline metabolism | ||||
| Histidine metabolism | ||||
| Tyrosine metabolism | ||||
| Phenylalanine metabolism | ||||
| Tryptophan metabolism | ||||
| Drug metabolism - cytochrome P450 | ||||
| Metabolic pathways | ||||
| Serotonergic synapse | ||||
| Dopaminergic synapse | ||||
| Cocaine addiction | ||||
| Amphetamine addiction | ||||
| Alcoholism | ||||
| Panther Pathway | Adrenaline and noradrenaline biosynthesis | |||
| 5-Hydroxytryptamine degredation | ||||
| Dopamine receptor mediated signaling pathway | ||||
| Pathway Interaction Database | Alpha-synuclein signaling | |||
| WikiPathways | Tryptophan metabolism | |||
| Dopamine metabolism | ||||
| Phase 1 - Functionalization of compounds | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Ultrasound promoted synthesis of 2-imidazolines in water: a greener approach toward monoamine oxidase inhibitors. Bioorg Med Chem Lett. 2009 Jan 15;19(2):546-9. | |||
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