Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00VUN
|
|||
| Drug Name |
TRX-818
|
|||
| Synonyms |
CVM-1118; ZRPWVAHVWBPHID-UHFFFAOYSA-L; TRX-818 sodium; TRX818; EX-A580; MolPort-044-567-575; CVM-1118(CVM1118); B5932; J-690105; (2'S,3R,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluorophenyl)-N-((1r,4R)-4-hydroxycyclohexyl)-2'-neopentyl-2-oxospiro[indoline-3,3'-pyrroli dine]-5'-carboxamide
Click to Show/Hide
|
|||
| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C00-D48; ICD-9: 140-199, 210-229] | Phase 1 | [1] | |
| Company |
TaiRx Taipei, Taiwan
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C16H11FNNa2O5P
|
|||
| Canonical SMILES |
COC1=C(C2=C(C=C1)NC(=CC2=O)C3=CC(=CC=C3)F)P(=O)([O-])[O-].[Na+].[Na+]
|
|||
| InChI |
1S/C16H13FNO5P.2Na/c1-23-14-6-5-11-15(16(14)24(20,21)22)13(19)8-12(18-11)9-3-2-4-10(17)7-9;;/h2-8H,1H3,(H,18,19)(H2,20,21,22);;/q;2*+1/p-2
|
|||
| InChIKey |
ZRPWVAHVWBPHID-UHFFFAOYSA-L
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Angiogenesis (AGG) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.