Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00RDE
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| Former ID |
DNC010203
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| Drug Name |
4-(4'-N-Methylphenyl)diazenylbenzenesulfonamide
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| Synonyms |
azo-sulfonamide, 1c; CHEMBL571371; BDBM33268; 4-[(E)-[4-(methylamino)phenyl]azo]benzenesulfonamide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C13H14N4O2S
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| Canonical SMILES |
CNC1=CC=C(C=C1)N=NC2=CC=C(C=C2)S(=O)(=O)N
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| InChI |
1S/C13H14N4O2S/c1-15-10-2-4-11(5-3-10)16-17-12-6-8-13(9-7-12)20(14,18)19/h2-9,15H,1H3,(H2,14,18,19)
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| InChIKey |
RMLHDMTUTOMVIX-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Carbonic anhydrase IX (CA-IX) | Target Info | Inhibitor | [1] |
| Carbonic anhydrase XII (CA-XII) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Nitrogen metabolism | |||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | |||
| Pathway Interaction Database | HIF-1-alpha transcription factor network | |||
| Reactome | Reversible hydration of carbon dioxide | |||
| Regulation of gene expression by Hypoxia-inducible Factor | ||||
| WikiPathways | Reversible Hydration of Carbon Dioxide | |||
| miR-targeted genes in muscle cell - TarBase | ||||
| miR-targeted genes in leukocytes - TarBase | ||||
| miR-targeted genes in epithelium - TarBase | ||||
| Vitamin D Receptor Pathway | ||||
| Regulation of Hypoxia-inducible Factor (HIF) by Oxygen | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Carbonic anhydrase inhibitors. Diazenylbenzenesulfonamides are potent and selective inhibitors of the tumor-associated isozymes IX and XII over the... Bioorg Med Chem. 2009 Oct 15;17(20):7093-9. | |||
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