Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D00LHT
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| Drug Name |
US9475795, 80
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| Synonyms |
SCHEMBL15548679; CHEMBL3891242; RXIULEDXXPGKEE-UHFFFAOYSA-N; BDBM250601; US9475795, 80; 4-(4-Chloro-2-fluorobenzyl)-1-((3,5-dimethyl-1H-pyrazol-4-yl)sulfonyl)-4-fluoropiperidine
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| Drug Type |
Small molecular drug
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| Structure |
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Download2D MOL |
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| Formula |
C17H20ClF2N3O2S
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| Canonical SMILES |
CC1=C(C(=NN1)C)S(=O)(=O)N2CCC(CC2)(CC3=C(C=C(C=C3)Cl)F)F
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| InChI |
1S/C17H20ClF2N3O2S/c1-11-16(12(2)22-21-11)26(24,25)23-7-5-17(20,6-8-23)10-13-3-4-14(18)9-15(13)19/h3-4,9H,5-8,10H2,1-2H3,(H,21,22)
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| InChIKey |
RXIULEDXXPGKEE-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Prokineticin receptor-1 (PROKR1) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Prokineticin receptor-1 (PROKR1) | Target's Patent Info | [1] | |
| Reactome | Peptide ligand-binding receptors | |||
| G alpha (q) signalling events | ||||
| WikiPathways | Gastrin-CREB signalling pathway via PKC and MAPK | |||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Sulfonyl piperidine derivatives and their use for treating prokineticin mediated diseases. US9475795. | |||
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