Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00LCE
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| Former ID |
DNC002635
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| Drug Name |
Antiproliferative Agent A771726
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| Synonyms |
AC1L1BPO; 2-cyano-3-hydroxy-n-(4-trifluoromethyl-phenyl)-butyramide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C12H11F3N2O2
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| Canonical SMILES |
CC(C(C#N)C(=O)NC1=CC=C(C=C1)C(F)(F)F)O
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| InChI |
1S/C12H11F3N2O2/c1-7(18)10(6-16)11(19)17-9-4-2-8(3-5-9)12(13,14)15/h2-5,7,10,18H,1H3,(H,17,19)/t7-,10-/m1/s1
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| InChIKey |
YODXEQNROKSLLQ-GMSGAONNSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Plasmodium Dihydroorotate dehydrogenase (Malaria DHOdehase) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Pyrimidine metabolism | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Pyrimidine Metabolism | |||
| Reactome | Pyrimidine biosynthesis | |||
| WikiPathways | Metabolism of nucleotides | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | |||
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