Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0K2PD
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| Former ID |
DNC000058
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| Drug Name |
3-aminobenzamide
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| Synonyms |
3-Aminobenzamide; 3544-24-9; m-Aminobenzamide; Benzamide, 3-amino-; 3-Amino-benzamide; Benzamide, m-amino-; meta-aminobenzamide; 3-ABA; 3-Aminobenzimide; 3-amino benzamide; aniline-3-carboxamide; 3-aminobenzoic acid amide; UNII-8J365YF1YH; CCRIS 3925; EINECS 222-586-9; NSC 36962; BRN 2802373; PARP Inhibitor I, 3-ABA; 3-H2NC6H4CONH2; CHEMBL81977; 3-AB; 8J365YF1YH; CHEBI:64042; GSCPDZHWVNUUFI-UHFFFAOYSA-N; MFCD00007989; 3-Aminobenzamide, 98%; SR-01000075657; HSDB 7581; 3-azanylbenzamide; m-amino benzamide; 4pml; 3-Aminobenzaminde
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1], [2] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C7H8N2O
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| Canonical SMILES |
C1=CC(=CC(=C1)N)C(=O)N
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| InChI |
1S/C7H8N2O/c8-6-3-1-2-5(4-6)7(9)10/h1-4H,8H2,(H2,9,10)
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| InChIKey |
GSCPDZHWVNUUFI-UHFFFAOYSA-N
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| CAS Number |
CAS 3544-24-9
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| PubChem Compound ID | ||||
| PubChem Substance ID |
93448, 623913, 3153929, 5671792, 8001804, 8150037, 8151216, 10519884, 11110713, 11113706, 11120346, 11120834, 11121322, 11121497, 11121977, 11335892, 11361131, 11362566, 11364386, 11364767, 11365128, 11366948, 11367329, 11367690, 11369510, 11369891, 11370403, 11370404, 11371922, 11372931, 11373291, 11374650, 11375491, 11375852, 11377672, 11378056, 11462103, 11485250, 11489393, 11490787, 11492910, 11495306, 12034999, 15090915, 17404607, 22391541, 24278206, 24855089, 26679244, 26751894
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| ChEBI ID |
CHEBI:64042
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Poly [ADP-ribose] polymerase 1 (PARP1) | Target Info | Inhibitor | [1], [2] |
| KEGG Pathway | Base excision repair | |||
| NF-kappa B signaling pathway | ||||
| Panther Pathway | FAS signaling pathway | |||
| Pathway Interaction Database | Integrin-linked kinase signaling | |||
| Caspase Cascade in Apoptosis | ||||
| Notch-mediated HES/HEY network | ||||
| Reactome | Dual Incision in GG-NER | |||
| WikiPathways | FAS pathway and Stress induction of HSP regulation | |||
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | ||||
| Nanoparticle triggered regulated necrosis | ||||
| Corticotropin-releasing hormone | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation. Nat Med. 2001 Jan;7(1):108-13. | |||
| REF 2 | Resistance-modifying agents. 5. Synthesis and biological properties of quinazolinone inhibitors of the DNA repair enzyme poly(ADP-ribose) polymeras... J Med Chem. 1998 Dec 17;41(26):5247-56. | |||
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