Drug Information
Drug General Information | Top | |||
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Drug ID |
D0GK7A
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Former ID |
DIB021129
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Drug Name |
UNC0638
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Synonyms |
UNC0638; 1255580-76-7; UNC-0638; UNC 0638; UNII-26A103L2FO; 2-Cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine; CHEMBL1231795; 26A103L2FO; 2-Cyclohexyl-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine; 1255517-77-1; 2-cyclohexyl-6-methoxy-N-[1-(propan-2-yl)piperidin-4-yl]-7-[3-(pyrrolidin-1-yl)propoxy]quinazolin-4-amine; 2-Cyclohexyl-N-(1-isopropyl-4-piperidinyl)-6-methoxy-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL
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Formula |
C30H47N5O2
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Canonical SMILES |
CC(C)N1CCC(CC1)NC2=NC(=NC3=CC(=C(C=C32)OC)OCCCN4CCCC4)C5CCCCC5
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InChI |
1S/C30H47N5O2/c1-22(2)35-17-12-24(13-18-35)31-30-25-20-27(36-3)28(37-19-9-16-34-14-7-8-15-34)21-26(25)32-29(33-30)23-10-5-4-6-11-23/h20-24H,4-19H2,1-3H3,(H,31,32,33)
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InChIKey |
QOECJCJVIMVJGX-UHFFFAOYSA-N
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CAS Number |
CAS 1255580-76-7
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PubChem Compound ID | ||||
PubChem Substance ID |
104247976, 119526857, 120486981, 123105095, 124899461, 136359814, 162011983, 163643279, 170474676, 172919806, 174007127, 174526899, 175608112, 178103594, 196409662, 198939535, 202033988, 210275208, 210280847, 223704808, 239813529, 241376938, 242060080, 249618148, 252157979, 252160542, 252319113, 252450239, 252481510, 252819802
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ChEBI ID |
CHEBI:95074
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Target and Pathway | Top | |||
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Target(s) | Euchromatic histone-lysine N-methyltransferase 1 (EHMT1) | Target Info | Inhibitor | [2] |
Histone-lysine N-methyltransferase EHMT2 (EHMT2) | Target Info | Inhibitor | [2] |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7015). | |||
REF 2 | A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells. Nat Chem Biol. 2011 Jul 10;7(8):566-74. |
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