Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08FKL
|
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| Former ID |
DIB013397
|
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| Drug Name |
ACHN-975
|
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| Indication | Pseudomonas infection [ICD-11: 1B92; ICD-10: A24, A24.0] | Phase 1 | [1] | |
| Company |
Achaogen
|
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| Structure |
 |
Download2D MOL |
||
| Formula |
C20H23N3O4
|
|||
| Canonical SMILES |
CC(C)(C(C(=O)NO)NC(=O)C1=CC=C(C=C1)C#CC#CC2CC2CO)N
|
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| InChI |
1S/C20H23N3O4/c1-20(2,21)17(19(26)23-27)22-18(25)14-9-7-13(8-10-14)5-3-4-6-15-11-16(15)12-24/h7-10,15-17,24,27H,11-12,21H2,1-2H3,(H,22,25)(H,23,26)/t15-,16+,17-/m1/s1
|
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| InChIKey |
GOCUUDXEOKIQRU-IXDOHACOSA-N
|
|||
| CAS Number |
CAS 1410809-36-7
|
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Haemophilus influenzae Acetylglucosamine deacetylase (Hae-influ lpxC) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT01870245) A Multiple Dose Study to Assess the Safety, Tolerability, and Pharmacokinetics of ACHN-975 in Healthy Volunteers. U.S. National Institutes of Health. | |||
| REF 2 | Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41. | |||
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