Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04QGH
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| Drug Name |
Piragliatin
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| Synonyms |
GK2; R1440; RO4389620
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Therapeutic Class |
Endocrine, nutritional and metabolic diseases
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| Structure |
 |
Download2D MOL |
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| Formula |
C19H20ClN3O4S
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| Canonical SMILES |
CS(=O)(=O)C1=C(C=C(C=C1)C(CC2CCC(=O)C2)C(=O)NC3=NC=CN=C3)Cl
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| InChI |
1S/C19H20ClN3O4S/c1-28(26,27)17-5-3-13(10-16(17)20)15(9-12-2-4-14(24)8-12)19(25)23-18-11-21-6-7-22-18/h3,5-7,10-12,15H,2,4,8-9H2,1H3,(H,22,23,25)/t12-,15+/m0/s1
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| InChIKey |
XEANIURBPHCHMG-SWLSCSKDSA-N
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| CAS Number |
CAS 625114-41-2
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Piragliatin (RO4389620), a novel glucokinase activator, lowers plasma glucose both in the postabsorptive state and after a glucose challenge in patients with type 2 diabetes mellitus: a mechanistic study.J Clin Endocrinol Metab.2010 Nov;95(11):5028-36. | |||
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