Resistance mutation info of drug
Drug General Information | ||||||||||||||||
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Drug ID | D0R3FP | |||||||||||||||
Drug Name | Tenofovir disoproxil fumarate | |||||||||||||||
Synonyms | Bis-POC-PMPA; GSK548470; PMPA-oral; Tenofovir DF; Tenozet; Viread | |||||||||||||||
Drug Type | Small molecular drug | |||||||||||||||
Therapeutic Class | Antiinfective Agents | |||||||||||||||
Structure | ||||||||||||||||
Drug Resistance Mutations | ||||||||||||||||
Target Name | HBV Reverse transcriptase | Target Info | ||||||||||||||
Uniprot ID | DPOL_HBVB5(347-690) | |||||||||||||||
Species | Hepatitis B virus genotype B (HBV-B) | |||||||||||||||
Reference Sequence |
EDWGPCTEHGEHRIRTPRTPARVTGGVFLVDKNPHNTTESRLVVDFSQFSRGNTRVSWPK FAVPNLQSLTNLLSSNLSWLSLDVSAAFYHLPLHPAAMPHLLVGSSGLSRYVARLSSNSR IINNQHRTMQNLHNSCSRNLYVSLMLLYKTYGRKLHLYSHPIILGFRKIPMGVGLSPFLL AQFTSAICSVVRRAFPHCLAFSYMDDVVLGAKSVQHLESLYAAVTNFLLSLGIHLNPHKT KRWGYSLNFMGYVIGSWGTLPQEHIVQKIKMCFRKLPVNRPIDWKVCQRIVGLLGFAAPF TQCGYPALMPLYACIQAKQAFTFSPTYKAFLSKQYLNLYPVARQ [Hepatitis B vi rus genotype B (HBV-B)] |
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Targeted Disease | HBV infection | |||||||||||||||
Drug Resistance Mutations |
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References | ||||||||||||||||
REF 1 | [Drug-resistant mutations in hepatitis B virus found in chronic HBV carriers using PCR sequencing technology]. Zhonghua Gan Zang Bing Za Zhi. 2016 Jan;24(1):36-9. |
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