Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T99009 | Target Info | |||
| Target Name | HUMAN dihydroorotate dehydrogenase (DHODH) | ||||
| Synonyms |
Dihydroorotate oxidase; Dihydroorotate dehydrogenase (quinone), mitochondrial; DHOdehase; DHODH
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| Gene Name | DHODH | ||||
| Biochemical Class | CH-CH donor oxidoreductase | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Cytochrome P450 1A2 (CYP1A2) | Co-Target | ||||
| UniProt ID | CP1A2_HUMAN | |||||
| Gene Name | CYP1A2 | |||||
| Synonyms |
Cholesterol 25-hydroxylase; Hydroperoxy icosatetraenoate dehydratase; CYPIA2; Cytochrome P(3)450; Cytochrome P450 4; Cytochrome P450-P3
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| Representative Drug(s) | Leflunomide | Drug Info | IC50 = 500 nM | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | DrugMatrix in vitro pharmacology data. National Toxicology Program | ||||
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