Co-Target(s) Information

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Target General Information
Co-Targets of This Target
References
Target General Information  Top
Target ID T89879 Target Info
Target Name SARS-CoV RNA-directed RNA polymerase (RdRp)
Synonyms
SARS-CoV RNA-directed RNA polymerase; SARS-CoV Pol; SARS-CoV RdRp; SARS-CoV nsp12 polymerase
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Gene Name SARS-CoV rep; SARS-CoV 1a-1b
Biochemical Class Coronaviruses polyprotein 1ab family
UniProt ID
R1AB_CVHSA (4370 - 5301)
Co-Targets of This Target  Top
Co-Target Name Purine nucleoside phosphorylase (PNP) Clinical trial Target
UniProt ID PNPH_HUMAN
Gene Name PNP
Synonyms
PNP; Inosine phosphorylase
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Representative Drug(s) Galidesivir Drug Info Ki = 33 nM [1]
References  Top
REF 1 The transition to magic bullets-transition state analogue drug design. Med. Chem. Commun. 2018;9:1983-1993.

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