Co-Target(s) Information
Target General Information | Top | ||||
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Target ID | T89658 | Target Info | |||
Target Name | MERS-CoV RNA-directed RNA polymerase (RdRp) | ||||
Synonyms |
MERS-CoV RNA-directed RNA polymerase; MERS-CoV Pol; MERS-CoV RdRp
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Gene Name | MERS-CoV rep; MERS-CoV 1a-1b | ||||
Biochemical Class | Coronaviruses polyprotein 1ab family | ||||
UniProt ID |
Co-Targets of This Target | Top | |||||
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Co-Target Name | Purine nucleoside phosphorylase (PNP) | Clinical trial Target | ||||
UniProt ID | PNPH_HUMAN | |||||
Gene Name | PNP | |||||
Synonyms |
PNP; Inosine phosphorylase
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Representative Drug(s) | Galidesivir | Drug Info | Ki = 33 nM | [1] |
References | Top | ||||
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REF 1 | The transition to magic bullets-transition state analogue drug design. Med. Chem. Commun. 2018;9:1983-1993. |
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