Co-Target(s) Information
Target General Information | Top | ||||
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Target ID | T86385 | Target Info | |||
Target Name | Cathepsin G (CTSG) | ||||
Synonyms |
CG
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Target Type | Clinical trial Target | ||||
Gene Name | CTSG | ||||
Biochemical Class | Peptidase | ||||
UniProt ID |
Co-Targets of This Target | Top | |||||
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Co-Target Name | Chymase (CYM) | Clinical trial Target | ||||
UniProt ID | CMA1_HUMAN | |||||
Gene Name | CMA1 | |||||
Synonyms |
Mast cell protease I; CYH; Alpha-chymase
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Representative Drug(s) | JNJ-10311795 | Drug Info | Ki = 2.3 nM | [1] |
References | Top | ||||
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REF 1 | Discovery of potent, selective, orally active, nonpeptide inhibitors of human mast cell chymase. J Med Chem. 2007 Apr 19;50(8):1727-30. |
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