Co-Target(s) Information
Target General Information | Top | ||||
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Target ID | T67282 | Target Info | |||
Target Name | Staphylococcus Leucyl-tRNA synthetase (Stap-coc leuS) | ||||
Synonyms |
Leucyl-tRNA synthetase; Leucine--tRNA ligase; LeuRS
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Target Type | Successful Target | ||||
Gene Name | Stap-coc leuS | ||||
Biochemical Class | Carbon-oxygen ligase | ||||
UniProt ID |
Co-Targets of This Target | Top | |||||
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Co-Target Name | Carbonic anhydrase II (CA-II) | Successful Target | ||||
UniProt ID | CAH2_HUMAN | |||||
Gene Name | CA2 | |||||
Synonyms |
Carbonic anhydrase C; Carbonic anhydrase 2; Carbonate dehydratase II; CAC
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Representative Drug(s) | Tavaborole | Drug Info | Ki = 462 nM | [1] |
References | Top | ||||
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REF 1 | Benzoxaboroles as Efficient Inhibitors of the beta-Carbonic Anhydrases from Pathogenic Fungi: Activity and Modeling Study. ACS Med Chem Lett. 2017 Oct 20;8(11):1194-8. |
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