Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05VGL
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| Former ID |
DIB003811
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| Drug Name |
Tavaborole
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| Synonyms |
Kerydin; AN2690; AN-2690; AN-2690); SCH-900340; Topical antifungal (onychomycosis), Merck & Co; Trichophyton-targeting antifungal (onychomycosis), Merck & Co; Fungal leucyl-tRNA synthetase inhibitor (onychomycosis), Anacor Pharmaceuticals/Schering-Plough; Fungal leucyl-tRNA synthetase inhibitor (onychomycosis), Merck & Co/Anacor; Trichophyton-targeting antifungal (onychomycosis), Anacor Pharmaceuticals/Schering-Plough
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| Drug Type |
Small molecular drug
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| Indication | Onychomycosis [ICD-11: EE12.1] | Approved | [1] | |
| Company |
Anacor; Anacor Pharmaceuticals Inc
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| Structure |
 |
Download2D MOL |
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| Formula |
C7H6BFO2
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| Canonical SMILES |
B1(C2=C(CO1)C=C(C=C2)F)O
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| InChI |
1S/C7H6BFO2/c9-6-1-2-7-5(3-6)4-11-8(7)10/h1-3,10H,4H2
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| InChIKey |
LFQDNHWZDQTITF-UHFFFAOYSA-N
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| CAS Number |
CAS 174671-46-6
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:77942
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| ADReCS Drug ID | BADD_D02119 | |||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Staphylococcus Leucyl-tRNA synthetase (Stap-coc leuS) | Target Info | Inhibitor | [1], [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | An antifungal agent inhibits an aminoacyl-tRNA synthetase by trapping tRNA in the editing site. Science. 2007 Jun 22;316(5832):1759-61. | |||
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