Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T59929 | Target Info | |||
| Target Name | Thymidine phosphorylase (TYMP) | ||||
| Synonyms |
TdRPase; TYMP; TP; Platelet-derived endothelial cell growth factor; PDECGF; PD-ECGF; Gliostatin
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| Target Type | Successful Target | ||||
| Gene Name | TYMP | ||||
| Biochemical Class | Pentosyltransferase | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Cytidine deaminase (CDA) | Clinical trial Target | ||||
| UniProt ID | CDD_HUMAN | |||||
| Gene Name | CDA | |||||
| Synonyms |
Cytidine aminohydrolase; CDA
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| Representative Drug(s) | Uridine | Drug Info | Ki = 0.0012 nM | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Carbocyclic analogues of the potent cytidine deaminase inhibitor 1-(beta-D-ribofuranosyl)-1,2-dihydropyrimidin-2-one (zebularine). J Med Chem. 1998 Jul 2;41(14):2572-8. | ||||
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