Co-Target(s) Information

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Target General Information
Co-Targets of This Target
References
Target General Information  Top
Target ID T30563 Target Info
Target Name Leukotriene B4 receptor 2 (LTB4R2)
Synonyms
Seven transmembrane receptor BLTR2; Leukotriene B4 receptor BLT2; Leukotriene B(4) receptor BLT2; LTB4-R2; LTB4-R 2; LTB4 receptor JULF2; BLTR2; BLT2R
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Target Type Clinical trial Target
Gene Name LTB4R2
Biochemical Class GPCR rhodopsin
UniProt ID
LT4R2_HUMAN
Co-Targets of This Target  Top
Co-Target Name Leukotriene B4 receptor 1 (LTB4R) Clinical trial Target
UniProt ID LT4R1_HUMAN
Gene Name LTB4R
Synonyms
P2Y7; P2Y purinoceptor 7; P2RY7; Leukotriene B(4) receptor BLT1; LTB4-R1; LTB4-R 1; LTB4-R; GPR16; G-protein coupled receptor 16; Chemoattractant receptor-like 1; CMKRL1; BLTR; BLT1; BLT
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Representative Drug(s) LTB4 Drug Info Ki = 0.12 nM Click to Show More [1]
2 Biomed 101 Drug Info IC50 = 1 nM [2]
References  Top
REF 1 Structural analogues of LY292728, a highly potent xanthone dicarboxylic acid leukotriene B4 receptor antagonist: spatial positioning of the secondary acid group. Bioorg Med Chem Lett. 1994 Sep 8;4(17):2077-82.
REF 2 Synthesis and pharmacological activity of SC-53228, a leukotriene B4 receptor antagonist with high intrinsic potency and selectivity. Bioorg Med Chem Lett. 1994 Mar 24;4(6):811-6.

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