Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T24626 | Target Info | |||
| Target Name | Haemophilus influenzae Acetylglucosamine deacetylase (Hae-influ lpxC) | ||||
| Synonyms |
UDP-3-O-acyl-N-acetylglucosamine deacetylase; UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase; Hae-influ UDP-3-O-acyl-GlcNAc deacetylase
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| Target Type | Clinical trial Target | ||||
| Gene Name | Hae-influ lpxC | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Pseudomonas UDP-3-O-acyl-GlcNAc deacetylase (Pseudo lpxC) | Literature-reported Target | ||||
| UniProt ID | LPXC_PSEAE | |||||
| Gene Name | Pseudo lpxC | |||||
| Synonyms |
Pseudo UDP-3-O-acyl-GlcNAc deacetylase; EnvA protein
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| Representative Drug(s) | ACHN-975 | Drug Info | IC50 = 0.02 nM | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Drug discovery strategies to outer membrane targets in Gram-negative pathogens. Bioorg Med Chem. 2016 Dec 15;24(24):6320-31. | ||||
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