Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T23145 | Target Info | |||
| Target Name | Cholesterol desmolase (CYP11A1) | ||||
| Synonyms |
P450(scc); Cytochrome P450(scc); Cytochrome P450 11A1; Cholesterol side-chain cleavage enzyme, mitochondrial; CYPXIA1; CYP11A
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| Target Type | Successful Target | ||||
| Gene Name | CYP11A1 | ||||
| Biochemical Class | Paired donor oxygen oxidoreductase | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Aromatase (CYP19A1) | Successful Target | ||||
| UniProt ID | CP19A_HUMAN | |||||
| Gene Name | CYP19A1 | |||||
| Synonyms |
P-450AROM; Estrogen synthetase; Estrogen synthase; Cytochrome P450 19A1; Cytochrome P-450AROM; CYPXIX; CYP19; CYAR; ARO1
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| Representative Drug(s) | Aminoglutethimide | Drug Info | IC50 = 5.2 nM | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Pharmacophore modeling strategies for the development of novel nonsteroidal inhibitors of human aromatase (CYP19). Bioorg Med Chem Lett. 2010 May 15;20(10):3050-64. | ||||
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