Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T18664 | Target Info | |||
| Target Name | Monoglyceride lipase (MAGL) | ||||
| Synonyms |
Monoacylglycerol lipase; MGL; Lysophospholipaselike; Lysophospholipase-like; Lysophospholipase homolog; HUK5; HU-K5
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| Target Type | Clinical trial Target | ||||
| Gene Name | MGLL | ||||
| Biochemical Class | Carboxylic ester hydrolase | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Monoacylglycerol lipase ABHD6 (ABHD6) | Patented-recorded Target | ||||
| UniProt ID | ABHD6_HUMAN | |||||
| Gene Name | ABHD6 | |||||
| Synonyms |
Abhydrolase domain-containing protein 6; 2-arachidonoylglycerol hydrolase
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| Representative Drug(s) | ABX-1431 | Drug Info | IC50 = 253 nM | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Identification of ABX-1431, a Selective Inhibitor of Monoacylglycerol Lipase and Clinical Candidate for Treatment of Neurological Disorders. J Med Chem. 2018 Oct 25;61(20):9062-9084. | ||||
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