Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T08922 | Target Info | |||
| Target Name | Acetyl-CoA carboxylase 2 (ACACB) | ||||
| Synonyms |
Acetyl-Coenzyme A carboxylase beta; Acetyl CoA carboxylase beta; ACCbeta; ACC2; ACC-beta; ACACB
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| Target Type | Successful Target | ||||
| Gene Name | ACACB | ||||
| Biochemical Class | Carbon-carbon ligase | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Acetyl-CoA carboxylase 1 (ACACA) | Co-Target | ||||
| UniProt ID | ACACA_HUMAN | |||||
| Gene Name | ACACA | |||||
| Synonyms |
ACC1; Acetyl-Coenzyme A carboxylase alpha; ACC-alpha
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| Representative Drug(s) | PF-05175157 | Drug Info | IC50 = 27 nM | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Decreasing the rate of metabolic ketone reduction in the discovery of a clinical acetyl-CoA carboxylase inhibitor for the treatment of diabetes. J Med Chem. 2014 Dec 26;57(24):10512-26. | ||||
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