Co-Target(s) Information
Target General Information | Top | ||||
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Target ID | T07289 | Target Info | |||
Target Name | Duffy antigen chemokine receptor (ACKR1) | ||||
Synonyms |
Plasmodium vivax receptor; GpFy; Glycoprotein D; Fy glycoprotein; Duffy antigen/chemokine receptor; DARC; CD234; ACKR1
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Target Type | Successful Target | ||||
Gene Name | ACKR1 | ||||
Biochemical Class | GPCR duffy | ||||
UniProt ID |
Co-Targets of This Target | Top | |||||
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Co-Target Name | Plasmodium Cysteine protease falcipain-2 (Malaria CPF2) | Literature-reported Target | ||||
UniProt ID | Q9N6S8_PLAFA | |||||
Gene Name | Malaria CPF2 | |||||
Synonyms |
Falcipain 2; Cysteine proteinase falcipain 2a
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Representative Drug(s) | Chloroquine | Drug Info | IC50 = 20 nM | [1] |
References | Top | ||||
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REF 1 | Designing novel inhibitors against falcipain-2 of Plasmodium falciparum. Bioorg Med Chem Lett. 2018 May 15;28(9):1566-1569. |
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