Drug Information
Drug General Information | Top | |||
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Drug ID |
D09EGZ
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Former ID |
DAP000165
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Drug Name |
Chloroquine
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Synonyms |
Amokin; Aralen; Aralen HCl; Arechin; Arechine; Arequin; Arolen; Arthrochin; Artrichin; Avlochlor; Avloclor; Bemaco; Bemaphate; Bemasulph; Benaquin; Bipiquin; CU-01000012392-2; Capquin; Chemochin; Chingamin; Chloraquine; Chlorochin; Chlorochine; Chlorochinum; Chloroin; Chloroquin; Chloroquina; Chloroquine (USP/INN); Chloroquine (VAN); Chloroquine Bis-Phosphoric Acid; Chloroquine FNA (TN); Chloroquine [USAN:INN:BAN]; Chloroquine phosphate; Chloroquinium; Chloroquinum; Chloroquinum [INN-Latin]; Chlorquin; Cidanchin; Clorochina; Clorochina [DCIT]; Cloroquina; Cloroquina [INN-Spanish]; Cocartrit; Dawaquin (TN); Delagil; Dichinalex; Elestol; Gontochin; Gontochin phosphate; Heliopar; Imagon; Ipsen 225; Iroquine; Khingamin; Klorokin; Lapaquin; Malaquin; Malaquin (*Diphosphate*); Malaren; Malarex; Mesylith; Miniquine; Neochin; Nivachine; Nivaquine B; Pfizerquine; Quinachlor; Quinagamin; Quinagamine; Quinercyl; Quingamine; Quinilon; Quinoscan; RP 3377; RP-3377; Resochen; Resochin; Resochin (TN); Resoquina; Resoquine; Reumachlor; Reumaquin; Rivoquine; Ro 01-6014/N2; Ronaquine; Roquine; SN 6718; SN-7618; ST 21; ST 21 (pharmaceutical); Sanoquin; Silbesan;Siragan; Solprina; Sopaquin; Tanakan; Tanakene; Tresochin; Trochin; W 7618;WIN 244
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Drug Type |
Small molecular drug
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Indication | Malaria [ICD-11: 1F40-1F45; ICD-10: B50-B64, B54] | Approved | [1], [2] | |
Therapeutic Class |
Antimalarials
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Company |
Medreich Sterilab Ltd
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Structure |
Download2D MOL |
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Formula |
C18H26ClN3
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Canonical SMILES |
CCN(CC)CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl
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InChI |
1S/C18H26ClN3/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21)
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InChIKey |
WHTVZRBIWZFKQO-UHFFFAOYSA-N
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CAS Number |
CAS 54-05-7
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PubChem Compound ID | ||||
PubChem Substance ID |
9827, 447935, 596572, 5050990, 7849425, 7978921, 8151759, 10526125, 11335579, 11360818, 11363006, 11365568, 11368130, 11371321, 11373917, 11376292, 11404351, 11405289, 11461790, 11466576, 11467696, 11483910, 11486252, 11487943, 11490157, 11492094, 11493946, 11528736, 14776983, 26675665, 29221876, 46506925, 47217037, 47291356, 47440521, 47440522, 47885638, 48035387, 48110720, 48185227, 48259487, 49635547, 49681217, 49698849, 49846799, 50111008, 53787949, 53788124, 56310729, 57321414
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ChEBI ID |
CHEBI:3638
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ADReCS Drug ID | BADD_D00440 ; BADD_D00441 | |||
SuperDrug ATC ID |
P01BA01
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SuperDrug CAS ID |
cas=000054057
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Drug Resistance Mutation (DRM) | Top | |||
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DRM | DRM Info |
Target and Pathway | Top | |||
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Target(s) | Duffy antigen chemokine receptor (ACKR1) | Target Info | Modulator | [3] |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5535). | |||
REF 2 | Opportunities and challenges in antiparasitic drug discovery. Nat Rev Drug Discov. 2005 Sep;4(9):727-40. | |||
REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. |
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