| Target Validation Information | |||||
|---|---|---|---|---|---|
| Target ID | T74258 | ||||
| Target Name | mRNA of PKC-zeta | ||||
| Target Type | Discontinued |
||||
| Drug Potency against Target | LY-326449 | Drug Info | IC50 = 8700 nM | [534154] | |
| BALANOL | Drug Info | IC50 = 3500 nM | |||
| References | |||||
| Ref 534154 | J Med Chem. 1996 Jul 5;39(14):2664-71.(S)-13-[(dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16, 21-dimetheno-1H, 13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H)-d ione (LY333531) and related analogues: isozyme selective inhibitors of protein kinase C beta. | ||||
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