Target Information

Target General Infomation
Target ID
T99031
Former ID
TTDC00164
Target Name
Dual specificity mitogen-activated protein kinase kinase
Synonyms
ERK activator kinase; MAP kinase kinase; MAPKK; MEK
Target Type
Clinical Trial
Disease Solid tumours [ICD9: 140-199, 210-229; ICD10: C00-D48]
Target Validation
T99031
Drugs and Mode of Action
Drug(s) GDC-0623 Drug Info Phase 1 Solid tumours [550794]
RG7304 Drug Info Phase 1 Solid tumours [548874]
Inhibitor GDC-0623 Drug Info [550794]
Modulator RG7304 Drug Info [551608]
References
Ref 548874Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800029782)
Ref 550794Clinical pipeline report, company report or official report of Genentech (2011).
Ref 550794Clinical pipeline report, company report or official report of Genentech (2011).
Ref 551608Clinical pipeline report, company report or official report of Roche.
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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