Target Information
| Target General Infomation | |||||
|---|---|---|---|---|---|
| Target ID |
T76522
|
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| Former ID |
TTDR01201
|
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| Target Name |
Pyridoxal kinase
|
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| Gene Name |
PDXK
|
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| Synonyms |
Pyridoxine kinase; PDXK
|
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| Target Type |
Research
|
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| Function |
Required for synthesisof pyridoxal-5-phosphate from vitamin B6.
|
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| BioChemical Class |
Kinase
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| UniProt ID | |||||
| EC Number |
EC 2.7.1.35
|
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| Sequence |
MEEECRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSD
ELQELYEGLRLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKW DGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGP DTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAM LLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSKRDI EDPEIVVQATVL |
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| Inhibitor | Adenosine-5'-Diphosphate | Drug Info | [1] | ||
| Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate | Drug Info | [2] | |||
| Pathways | |||||
| BioCyc Pathway | Pyridoxal 5' | ||||
| -phosphate salvage | |||||
| KEGG Pathway | Vitamin B6 metabolism | ||||
| Metabolic pathways | |||||
| NetPath Pathway | FSH Signaling Pathway | ||||
| PANTHER Pathway | Pyridoxal phosphate salvage pathway | ||||
| Vitamin B6 metabolism | |||||
| PathWhiz Pathway | Vitamin B6 Metabolism | ||||
| WikiPathways | Metabolism of water-soluble vitamins and cofactors | ||||
| References | |||||
| REF 1 | DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-4. Nucleic Acids Res. 2011 January | ||||
| REF 2 | How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | ||||
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