Target Information
| Target General Infomation | |||||
|---|---|---|---|---|---|
| Target ID |
T61997
|
||||
| Former ID |
TTDR00362
|
||||
| Target Name |
20S proteasome
|
||||
| Synonyms |
MCP; Multicatalytic protease
|
||||
| Target Type |
Successful
|
||||
| Disease | Mantle cell lymphoma [ICD9: 200.4, 202.8, 203.0, 208.9; ICD10: C81-C86, C85.7, C90.0, C91-C95] | ||||
| BioChemical Class |
Peptidase
|
||||
| EC Number |
EC 3.4.25.1
|
||||
| Drugs and Mode of Action | |||||
| Drug(s) | PS-341 | Drug Info | Approved | Mantle cell lymphoma | [1], [2] |
| Inhibitor | PS-341 | Drug Info | [3] | ||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007364) | ||||
| REF 2 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | ||||
| REF 3 | Selected novel anticancer treatments targeting cell signaling proteins. Oncologist. 2001;6(6):517-37. | ||||
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