Target General Information
Target ID T93566
Target Name mRNA of ALOX5
Synonyms 5LO (mRNA); 5lipoxygenase (mRNA); ALOX5 (mRNA); Arachidonate 5lipoxygenase (mRNA); ALOX5
Target Type Discontinued
Gene Name ALOX5
Biochemical Class Oxidoreductases acting on single donors
UniProt ID LOX5_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Asthma
Example drug ZD-2138 Discontinued in Phase 2 [545000], [1572592]
Tissue Nasal and bronchial airway
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 0.14
Z-score: 0.28
P-value: 9.43E-03
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 545000Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001835)
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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