Target expression details
Target General Information | |||||
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Target ID | T93566 | ||||
Target Name | mRNA of ALOX5 | ||||
Synonyms | 5LO (mRNA); 5lipoxygenase (mRNA); ALOX5 (mRNA); Arachidonate 5lipoxygenase (mRNA); ALOX5 | ||||
Target Type | Discontinued | ||||
Gene Name | ALOX5 | ||||
Biochemical Class | Oxidoreductases acting on single donors | ||||
UniProt ID | LOX5_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Asthma | ||||
Example drug | ZD-2138 | Discontinued in Phase 2 | [545000], [1572592] | ||
Tissue | Nasal and bronchial airway | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: 0.14 Z-score: 0.28 P-value: 9.43E-03 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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