Target General Information
Target ID	T89041
Target Name	Steroid 17-alpha-monooxygenase
Synonyms	17 alpha-Hydroxylase/C17-20-lyase; CYP 17; CYPXVII; P450 17; P450-C17; P450c17; Steroid 17-alpha-hydroxylase/17,20 lyase; CYP17A1
Target Type	Successful
Gene Name	CYP17A1
Biochemical Class	Oxidoreductases acting on paired donors
UniProt ID	CP17A_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Prostate cancer
Example drug	Abiraterone acetate			Approved	[551871], [1572592]
Tissue	Prostate
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: 0.07 Z-score: 0.21 P-value: 6.87E-01
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 551871	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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