Target expression details
Target General Information | |||||
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Target ID | T85467 | ||||
Target Name | Prostaglandin E2 receptor EP3 | ||||
Synonyms | PGE receptor, EP3 subtype; PGE2-R; Prostanoid EP3 receptor; PTGER3 | ||||
Target Type | Clinical Trial | ||||
Gene Name | PTGER3 | ||||
Biochemical Class | GPCR rhodopsin | ||||
UniProt ID | PE2R3_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Asthma | ||||
Example drug | GR-63799X | Discontinued in Phase 1 | [539236], [545501], [1572592] | ||
Tissue | Nasal and bronchial airway | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: 7.51E-03 Z-score: 0.03 P-value: 4.36E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
Reference | |||||
Ref 545501 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003508) |
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