Target General Information
Target ID T74238
Target Name Leukotriene CysLT2 receptor
Synonyms CysLTR2; Cysteinyl leukotriene receptor 2; Gprotein coupled receptor GPCR21; Gprotein coupled receptor HG57; HPN321; hGPCR21; CYSLTR2
Target Type Clinical Trial
Gene Name CYSLTR2
Biochemical Class GPCR rhodopsin
UniProt ID CLTR2_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Asthma
Example drug BAY-X-7195 Phase 2 [545585], [1572592]
Tissue Nasal and bronchial airway
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.24
Z-score: -0.52
P-value: 1.40E-03
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 545585Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003794)
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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