Target General Information
Target ID T72458
Target Name Melanocortin-4 receptor
Synonyms MC4-R; MC4R
Target Type Clinical Trial
Gene Name MC4R
Biochemical Class GPCR rhodopsin
UniProt ID MC4R_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Type 2 diabetes
Example drug Melanotetan II Preclinical [536122], [1572592]
Tissue Liver tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.04
Z-score: -0.18
P-value: 5.64E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 536122Emerging drugs for obesity: linking novel biological mechanisms to pharmaceutical pipelines. Expert Opin Emerg Drugs. 2005 Aug;10(3):643-60.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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