Target expression details
Target General Information | |||||
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Target ID | T52921 | ||||
Target Name | Nociceptin receptor | ||||
Synonyms | KOR-3; Kappa-type 3 opioid receptor; OP(4); ORL-1; ORL-1 receptor; Opioid receptor 4; Opioid receptor like-1 receptor; Opioid-receptor-like 1; Orphanin FQ receptor; OPRL1 | ||||
Target Type | Clinical Trial | ||||
Gene Name | OPRL1 | ||||
Biochemical Class | GPCR rhodopsin | ||||
UniProt ID | OPRX_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Depression | ||||
Example drug | LY-2940094 | Phase 2 | [524117], [1572592] | ||
Tissue | Pre-frontal cortex | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: 0.05 Z-score: 0.25 P-value: 1.75E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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