Target expression details
Target General Information | |||||
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Target ID | T48873 | ||||
Target Name | Synaptic vesicle amine transporter | ||||
Synonyms | Monoamine transporter; Solute carrier family 18 member 2; VAT; VMAT; Vesicular Monoamine Transporter ; Vesicular amine transporter; SLC18A2 | ||||
Target Type | Successful | ||||
Gene Name | SLC18A2 | ||||
Biochemical Class | Major facilitator superfamily | ||||
UniProt ID | VMAT2_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Alzheimer's disease | ||||
Example drug | AV 133 | Phase 3 | [548627], [1572592] | ||
Tissue | Entorhinal cortex | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.04 Z-score: -0.11 P-value: 2.69E-02 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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