Target General Information
Target ID	T29960
Target Name	Wilms tumor protein
Synonyms	WT1 protein; WT33; Wilms' tumour 1 protein; WT1
Target Type	Clinical Trial
Gene Name	WT1
Biochemical Class	EGR C2H2-type zinc-finger
UniProt ID	WT1_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Acute myelocytic leukemia
Example drug	Combined PR1/WT1 vaccine			Phase 2	[533145], [1572592]
Tissue	Bone marrow
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: 1.54 Z-score: 7.84 P-value: 5.12E-79
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 533145	Review of the Results of WT1 Peptide Vaccination Strategies for Myelodysplastic Syndromes and Acute Myeloid Leukemia from Nine Different Studies. Front Immunol. 2015 Feb 4;6:36.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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