Target expression details
Target General Information | |||||
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Target ID | T26368 | ||||
Target Name | GABA(A) receptor alpha-5 | ||||
Synonyms | GABA-A alpha-5; GABAA alpha 5; GABRA5 | ||||
Target Type | Clinical Trial | ||||
Gene Name | GABRA5 | ||||
Biochemical Class | Ligand-gated ion channel | ||||
UniProt ID | GBRA5_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Alzheimer's disease | ||||
Example drug | RG-1662 | Phase 2 | [525248], [1572592] | ||
Tissue | Entorhinal cortex | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.68 Z-score: -0.61 P-value: 3.15E-09 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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