Target expression details
Target General Information | |||||
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Target ID | T01777 | ||||
Target Name | Alpha-2C adrenergic receptor | ||||
Synonyms | Alpha-2C adrenoceptor; Alpha-2C adrenoreceptor; Subtype C4; ADRA2C | ||||
Target Type | Successful | ||||
Gene Name | ADRA2C | ||||
Biochemical Class | GPCR rhodopsin | ||||
UniProt ID | ADA2C_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Alzheimer's disease | ||||
Example drug | ORM-12741 | Phase 2 | [525230], [1572592] | ||
Tissue | Entorhinal cortex | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.06 Z-score: -0.28 P-value: 1.76E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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